Aβ Oligomers and Fibrillar Aggregates Induce Different Apoptotic Pathways in LAN5 Neuroblastoma Cell Cultures

Fibril deposit formation of amyloid β-protein (Aβ) in the brain is a hallmark of Alzheimer's disease (AD). Increasing evidence suggests that toxicity is linked to diffusible Aβ oligomers, which have been found in soluble brain extracts of AD patients, rather than to insoluble fibers. Here we re...

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Bibliographische Detailangaben
Hauptverfasser: Picone, Pasquale, Carrotta, Rita, Montana, Giovanna, Nobile, Maria Rita, San Biagio, Pier Luigi, Di Carlo, Marta
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2009
Schlagworte:
Protein
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2712196/
https://ncbi.nlm.nih.gov/pubmed/19450490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2008.11.056
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