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Investigation of transcriptional gene silencing and mechanism induced by shRNAs targeted to RUNX3 in vitro
AIM: To investigate transcriptional gene silencing induced by short hairpin RNAs (shRNAs) that target gene prompter regions of RUNX3 gene, and whether shRNAs homologous to DNA sequences may serve as initiators for methylation. METHODS: According to the principle of RNAi design, pSilencer3.1-H1-shRNA...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The WJG Press and Baishideng
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2712167/ https://ncbi.nlm.nih.gov/pubmed/18494051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.14.3006 |
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