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G-protein signalling negatively regulates the stability of aryl hydrocarbon receptor
Aryl hydrocarbon receptor (AhR) is a transcription factor that works as a dioxin receptor and is also involved in various physiological phenomena, including development and cell proliferation. Here, we show that the Gα(13) signal destabilizes AhR by promoting the ubiquitination of AhR. Gα(13) intera...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2711834/ https://ncbi.nlm.nih.gov/pubmed/19390533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2009.35 |
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