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Platelet-activating factor induces the processing of nuclear factor-κB p105 into p50, which mediates acute bowel injury in mice
Platelet-activating factor (PAF), an endogenous proinflammatory phospholipid, when injected intravascularly to rats and mice, causes shock, acute bowel injury, and a rapid activation of NF-κB p50-p50 with upregulation of the chemokine CXCL2 in the intestine. In this study, we investigate the mechani...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Physiological Society
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2711750/ https://ncbi.nlm.nih.gov/pubmed/19460845 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00053.2009 |
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