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Function and regulation of TRPP2 at the plasma membrane
The vast majority (∼99%) of all known cases of autosomal dominant polycystic kidney disease (ADPKD) are caused by naturally occurring mutations in two separate, but genetically interacting, loci, pkd1 and pkd2. pkd1 encodes a large multispanning membrane protein (PKD1) of unknown function, while pkd...
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| Hovedforfatter: | |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Physiological Society
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2711710/ https://ncbi.nlm.nih.gov/pubmed/19244406 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.90277.2008 |
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