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PKD2 Functions as an Epidermal Growth Factor-Activated Plasma Membrane Channel
PKD2, or polycystin 2, the product of the gene mutated in type 2 autosomal dominant polycystic kidney disease, belongs to the transient receptor potential channel superfamily and has been shown to function as a nonselective cation channel in the plasma membrane. However, the mechanism of PKD2 activa...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1234340/ https://ncbi.nlm.nih.gov/pubmed/16135816 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.18.8285-8298.2005 |
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