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PKD2 Functions as an Epidermal Growth Factor-Activated Plasma Membrane Channel

PKD2, or polycystin 2, the product of the gene mutated in type 2 autosomal dominant polycystic kidney disease, belongs to the transient receptor potential channel superfamily and has been shown to function as a nonselective cation channel in the plasma membrane. However, the mechanism of PKD2 activa...

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Detalhes bibliográficos
Main Authors: Ma, Rong, Li, Wei-Ping, Rundle, Dana, Kong, Jin, Akbarali, Hamid I., Tsiokas, Leonidas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1234340/
https://ncbi.nlm.nih.gov/pubmed/16135816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.18.8285-8298.2005
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