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RAD51C facilitates checkpoint signaling by promoting CHK2 phosphorylation

The RAD51 paralogues act in the homologous recombination (HR) pathway of DNA repair. Human RAD51C (hRAD51C) participates in branch migration and Holliday junction resolution and thus is important for processing HR intermediates late in the DNA repair process. Evidence for early involvement of RAD51...

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Détails bibliographiques
Auteurs principaux: Badie, Sophie, Liao, Chunyan, Thanasoula, Maria, Barber, Paul, Hill, Mark A., Tarsounas, Madalena
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711581/
https://ncbi.nlm.nih.gov/pubmed/19451272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200811079
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