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VE-PTP controls blood vessel development by balancing Tie-2 activity

Vascular endothelial protein tyrosine phosphatase (VE-PTP) is an endothelial-specific receptor-type tyrosine phosphatase that associates with Tie-2 and VE-cadherin. VE-PTP gene disruption leads to embryonic lethality, vascular remodeling defects, and enlargement of vascular structures in extraembryo...

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Autors principals: Winderlich, Mark, Keller, Linda, Cagna, Giuseppe, Broermann, Andre, Kamenyeva, Olena, Kiefer, Friedemann, Deutsch, Urban, Nottebaum, Astrid F., Vestweber, Dietmar
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711575/
https://ncbi.nlm.nih.gov/pubmed/19451274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200811159
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