The recycling and transcytotic pathways for IgG transport by FcRn are distinct and display an inherent polarity

The Fc receptor FcRn traffics immunoglobulin G (IgG) in both directions across polarized epithelial cells that line mucosal surfaces, contributing to host defense. We show that FcRn traffics IgG from either apical or basolateral membranes into the recycling endosome (RE), after which the actin motor...

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Detalhes bibliográficos
Main Authors: Tzaban, Salit, Massol, Ramiro H., Yen, Elizabeth, Hamman, Wendy, Frank, Scott R., Lapierre, Lynne A., Hansen, Steen H., Goldenring, James R., Blumberg, Richard S., Lencer, Wayne I.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2009
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711563/
https://ncbi.nlm.nih.gov/pubmed/19451275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200809122
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