Ca(2+)-dependent Calmodulin Binding to FcRn Affects Immunoglobulin G Transport in the Transcytotic Pathway

The Fcγ receptor FcRn transports immunoglobulin G (IgG) so as to avoid lysosomal degradation and to carry it bidirectionally across epithelial barriers to affect mucosal immunity. Here, we identify a calmodulin-binding site within the FcRn cytoplasmic tail that affects FcRn trafficking. Calmodulin b...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Dickinson, Bonny L., Claypool, Steven M., D'Angelo, June A., Aiken, Martha L., Venu, Nanda, Yen, Elizabeth H., Wagner, Jessica S., Borawski, Jason A., Pierce, Amy T., Hershberg, Robert, Blumberg, Richard S., Lencer, Wayne I.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2008
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174181/
https://ncbi.nlm.nih.gov/pubmed/18003977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-07-0658
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados