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Aggregation of Membrane Proteins by Cytosolic Cross-Linkers: Theory and Simulation of the LAT-Grb2-SOS1 System

Ligand-induced receptor aggregation is a well-known mechanism for initiating intracellular signals but oligomerization of distal signaling molecules may also be required for signal propagation. Formation of complexes containing oligomers of the transmembrane adaptor protein, linker for the activatio...

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Autors principals: Nag, Ambarish, Monine, Michael I., Faeder, James R., Goldstein, Byron
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711295/
https://ncbi.nlm.nih.gov/pubmed/19348745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.01.019
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