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Aggregation of Membrane Proteins by Cytosolic Cross-Linkers: Theory and Simulation of the LAT-Grb2-SOS1 System

Ligand-induced receptor aggregation is a well-known mechanism for initiating intracellular signals but oligomerization of distal signaling molecules may also be required for signal propagation. Formation of complexes containing oligomers of the transmembrane adaptor protein, linker for the activatio...

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Detalhes bibliográficos
Main Authors: Nag, Ambarish, Monine, Michael I., Faeder, James R., Goldstein, Byron
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711295/
https://ncbi.nlm.nih.gov/pubmed/19348745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.01.019
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