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Model Discrimination and Mechanistic Interpretation of Kinetic Data in Protein Aggregation Studies

Given the importance of protein aggregation in amyloid diseases and in the manufacture of protein pharmaceuticals, there has been increased interest in measuring and modeling the kinetics of protein aggregation. Several groups have analyzed aggregation data quantitatively, typically measuring aggreg...

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Detalhes bibliográficos
Main Authors: Bernacki, Joseph P., Murphy, Regina M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711288/
https://ncbi.nlm.nih.gov/pubmed/19348769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2008.12.3903
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