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Bioinformatic analysis of xenobiotic reactive metabolite target proteins and their interacting partners

BACKGROUND: Protein covalent binding by reactive metabolites of drugs, chemicals and natural products can lead to acute cytotoxicity. Recent rapid progress in reactive metabolite target protein identification has shown that adduction is surprisingly selective and inspired the hope that analysis of t...

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Autors principals: Fang, Jianwen, Koen, Yakov M, Hanzlik, Robert P
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711050/
https://ncbi.nlm.nih.gov/pubmed/19523227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6769-9-5
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