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Hidden Markov models for the assessment of chromosomal alterations using high-throughput SNP arrays

Chromosomal DNA is characterized by variation between individuals at the level of entire chromosomes (e.g. aneuploidy in which the chromosome copy number is altered), segmental changes (including insertions, deletions, inversions, and translocations), and changes to small genomic regions (including...

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Detalhes bibliográficos
Principais autores: Scharpf, Robert B., Parmigiani, Giovanni, Pevsner, Jonathan, Ruczinski, Ingo
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2710854/
https://ncbi.nlm.nih.gov/pubmed/19609370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1214/07-AOAS155
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