Combinatorial roles for pRB, p107, and p130 in E2F-mediated cell cycle control

Numerous studies have implicated the pRB family of nuclear proteins in the control of cell cycle progression. Although over-expression experiments have revealed that each of these proteins, pRB, p107, and p130, can induce a G(1) cell cycle arrest, mouse knockouts demonstrated distinct developmental...

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Bibliographic Details
Main Authors: Classon, Marie, Salama, Sofie, Gorka, Carolyn, Mulloy, Roseann, Braun, Pascal, Harlow, Ed
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2000
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC27107/
https://ncbi.nlm.nih.gov/pubmed/10995475
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