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Solution structure of the silkworm βGRP/GNBP3 N-terminal domain reveals the mechanism for β-1,3-glucan-specific recognition

The β-1,3-glucan recognition protein (βGRP)/Gram-negative bacteria-binding protein 3 (GNBP3) is a crucial pattern-recognition receptor that specifically binds β-1,3-glucan, a component of fungal cell walls. It evokes innate immunity against fungi through activation of the prophenoloxidase (proPO) ca...

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Detalhes bibliográficos
Main Authors: Takahasi, Kiyohiro, Ochiai, Masanori, Horiuchi, Masataka, Kumeta, Hiroyuki, Ogura, Kenji, Ashida, Masaaki, Inagaki, Fuyuhiko
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2710696/
https://ncbi.nlm.nih.gov/pubmed/19561300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0901671106
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