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Functional implications of multistage copper binding to the prion protein

The prion protein (PrP) is responsible for a group of neurodegenerative diseases called the transmissible spongiform encephalopathies. The normal function of PrP has not yet been discovered, but indirect evidence suggests a linkage to its ability to bind copper. In this article, low-copper-concentra...

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Detalhes bibliográficos
Main Authors: Hodak, Miroslav, Chisnell, Robin, Lu, Wenchang, Bernholc, J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2710693/
https://ncbi.nlm.nih.gov/pubmed/19561303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903807106
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