Secretory phospholipase A2-IID is an effector molecule of CD4(+)CD25(+) regulatory T cells

Suppression by natural CD4(+)CD25(+) regulatory T cells (Tregs) is one mechanism by which tolerance is maintained. However, the way in which Tregs mediate suppression is not well understood. Here, we show that secreted phospholipase A2 (sPLA2)-IID is selectively produced by Tregs. sPLA2-IID is a pot...

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Bibliografiska uppgifter
Huvudupphovsmän: von Allmen, Caroline E., Schmitz, Nicole, Bauer, Monika, Hinton, Heather J., Kurrer, Michael O., Buser, Regula B., Gwerder, Myriam, Muntwiler, Simone, Sparwasser, Tim, Beerli, Roger R., Bachmann, Martin F.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2009
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2710677/
https://ncbi.nlm.nih.gov/pubmed/19564598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812569106
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