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Isolation of active regulatory elements from eukaryotic chromatin using FAIRE (Formaldehyde Assisted Isolation of Regulatory Elements)

The binding of sequence-specific regulatory factors and the recruitment of chromatin remodeling activities cause nucleosomes to be evicted from chromatin in eukaryotic cells. Traditionally, these active sites have been identified experimentally through their sensitivity to nucleases. Here we describ...

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Main Authors: Giresi, Paul G., Lieb, Jason D.
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2710428/
https://ncbi.nlm.nih.gov/pubmed/19303047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2009.03.003
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