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β8 integrins are required for vascular morphogenesis in mouse embryos
In order to assess the in vivo function of integrins containing the β8 subunit, we have generated integrin β8- deficient mice. Ablation of β8 results in embryonic or perinatal lethality with profound defects in vascular development. Sixty-five percent of integrin β8-deficient embryos die at midgesta...
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| Glavni autori: | , , , , , |
|---|---|
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2002
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2710098/ https://ncbi.nlm.nih.gov/pubmed/12050137 |
| Oznake: |
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