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Integrin α8β1 Is Critically Important for Epithelial–Mesenchymal Interactions during Kidney Morphogenesis
We present genetic evidence that integrins regulate epithelial–mesenchymal interactions during organogenesis. Mice with a mutation in the α8 gene do not express the integrin α8β1 and exhibit profound deficits in kidney morphogenesis. In wild-type animals, inductive interactions between the ureteric...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2711892/ https://ncbi.nlm.nih.gov/pubmed/9054500 |
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