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A New Strategy for the Synthesis of Substituted Morpholines
[Image: see text] A four-step synthesis of cis-3,5-disubstituted morpholines from enantiomerically pure amino alcohols is described. The key step in the synthesis is a Pd-catalyzed carboamination reaction between a substituted ethanolamine derivative and an aryl or alkenyl bromide. The morpholine pr...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2709957/ https://ncbi.nlm.nih.gov/pubmed/19480462 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo9007223 |
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