Laddar...
Purinergic P2X(7) receptors regulate secretion of interleukin-1 receptor antagonist and beta cell function and survival
AIMS/HYPOTHESIS: In obesity, beta cells activate compensatory mechanisms to adapt to the higher insulin demand. Interleukin-1 receptor antagonist (IL-1Ra) prevents obesity-induced hyperglycaemia and is a potent target for the treatment of diabetes, but the mechanisms of its secretion and regulation...
Sparad:
| Huvudupphovsmän: | , , , , , |
|---|---|
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Springer-Verlag
2009
|
| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2709906/ https://ncbi.nlm.nih.gov/pubmed/19396427 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-009-1349-0 |
| Taggar: |
Lägg till en tagg
Inga taggar, Lägg till första taggen!
|