The Antiinflammatory Cytokine Interleukin-1 Receptor Antagonist Protects from High-Fat Diet-Induced Hyperglycemia

Subclinical inflammation is a recently discovered phenomenon in type 2 diabetes. Elevated cytokines impair β-cell function and survival. A recent clinical trial shows that blocking IL-1β signaling by IL-1 receptor antagonist (IL-1Ra) improves β-cell secretory function in patients with type 2 diabete...

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Main Authors: Sauter, Nadine S., Schulthess, Fabienne T., Galasso, Ryan, Castellani, Lawrence W., Maedler, Kathrin
Format: Artigo
Jezik:Inglês
Izdano: The Endocrine Society 2008
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2734491/
https://ncbi.nlm.nih.gov/pubmed/18239070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2007-1059
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