How does a β-hairpin fold/unfold? Competition between topology and heterogeneity in a solvable model
We study the competition between topological effects and sequence inhomogeneities in determining the thermodynamics and the un/folding kinetics of a β-hairpin. Our work utilizes a new exactly solvable model that allows for arbitrary configurations of native contacts. In general, the competition betw...
Uloženo v:
| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2000
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC27099/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10995462/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.190103297 |
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