LIGHT signals directly to intestinal epithelia to cause barrier dysfunction via cytoskeletal and endocytic mechanisms

BACKGROUND & AIMS: LIGHT (lymphotoxin-like inducible protein that competes with glycoprotein D for herpes virus entry on T cells) is a TNF core family member that regulates T cell activation and causes experimental inflammatory bowel disease. Additional data suggest that LIGHT may be involved in...

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Main Authors: Schwarz, Brad T., Wang, Fengjun, Shen, Le, Clayburgh, Daniel R., Su, Liping, Wang, Yingmin, Fu, Yang-Xin, Turner, Jerrold R.
Format: Artigo
Language:Inglês
Published: 2007
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709832/
https://ncbi.nlm.nih.gov/pubmed/17570213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2007.02.052
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