Bortezomib-induced enzyme-targeted radiotherapy in herpesvirus-associated tumors

We investigated the possibility of using a pharmacologic agent to modulate viral gene expression in order to target radiotherapy to tumor tissue. In a murine xenograft model, we had previously shown targeting of [(125)I]2'-fluoro-2'-deoxy-beta-D-5-iodouracilarabinofuranoside ([(125)I]FIAU)...

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Hauptverfasser: Fu, De-Xue, Tanhehco, Yvette, Chen, Jianmeng, Foss, Catherine A., Fox, James J., Chong, Ja-Mun, Hobbs, Robert F., Fukayama, Masashi, Sgouros, George, Kowalski, Jeanne, Pomper, Martin G., Ambinder, Richard F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709824/
https://ncbi.nlm.nih.gov/pubmed/18776891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.1864
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