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An Improved Synthesis of α,β-Unsaturated Nitrones Relevant to the Stephacidins and Analogs Thereof

A new method is reported for the synthesis of the α,β-unsaturated nitrone moiety characteristic of the stephacidin/avrainvillamide family of bioactive prenylated indole alkaloids. Application to the synthesis of stephacidin analogs and a potential biological probe are showcased.

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Detalhes bibliográficos
Main Authors: Hafensteiner, Benjamin D., Santamarina, Mariá E., Petricci, Elena, Baran, Phil S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709696/
https://ncbi.nlm.nih.gov/pubmed/19423345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2009.04.045
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