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A novel α,β-unsaturated nitrone-aryne [3+2] cycloaddition and its application in the synthesis of the cortistatin core

We describe here a novel α,β-unsaturated nitrone-aryne [3+2] cycloaddition. The resulting benzoisoxazolines underwent N-O bond reduction–elimination–electrocyclization sequence to furnish a variety of polysubstituted 2H or 2-alkylated-1-benzo-pyrans. The application of this methodology was further d...

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Bibliografiska uppgifter
Huvudupphovsmän: Dai, Mingji, Wang, Zhang, Danishefsky, Samuel J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2598426/
https://ncbi.nlm.nih.gov/pubmed/19924220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2008.09.019
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