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Structure-activity relationship analysis of cytotoxic cyanoguanidines: selection of CHS 828 as candidate drug
BACKGROUND: N-(6-(4-chlorophenoxy)hexyl)-N'-cyano-N''-4-pyridyl guanidine) (CHS 828) is the first candidate drug from a novel group of anti-tumour agents – the pyridyl cyanoguanidines, shown to be potent compounds interfering with cellular metabolism (inhibition of nicotinamide phosph...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2709656/ https://ncbi.nlm.nih.gov/pubmed/19563661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-2-114 |
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