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Analyzing the forces binding a restriction endonuclease to DNA using a synthetic nanopore
Restriction endonucleases are used prevalently in recombinant DNA technology because they bind so stably to a specific target sequence and, in the presence of cofactors, cleave double-helical DNA specifically at a target sequence at a high rate. Using synthetic nanopores along with molecular dynamic...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2709577/ https://ncbi.nlm.nih.gov/pubmed/19433506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp317 |
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