Highly efficient incorporation of the fluorescent nucleotide analogs tC and tC(O) by Klenow fragment

Studies of the mechanisms by which DNA polymerases select the correct nucleotide frequently employ fluorescently labeled DNA to monitor conformational rearrangements of the polymerase–DNA complex in response to incoming nucleotides. For this purpose, fluorescent base analogs play an increasingly imp...

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Bibliographic Details
Main Authors: Sandin, Peter, Stengel, Gudrun, Ljungdahl, Thomas, Börjesson, Karl, Macao, Bertil, Wilhelmsson, L. Marcus
Format: Artigo
Language:Inglês
Published: Oxford University Press 2009
Subjects:
Molecular Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709563/
https://ncbi.nlm.nih.gov/pubmed/19401439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp266
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