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Targeted G-protein inhibition as a novel approach to decrease vagal atrial fibrillation by selective parasympathetic attenuation
AIMS: The parasympathetic nervous system is thought to play a key role in atrial fibrillation (AF). Since parasympathetic signalling is primarily mediated by the heterotrimeric G-protein, Gα(i)βγ, we hypothesized that targeted inhibition of Gα(i) interactions in the posterior left atrium (PLA) would...
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| Autors principals: | , , , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2709464/ https://ncbi.nlm.nih.gov/pubmed/19457892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvp148 |
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