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Rho kinase-1 mediates cardiac fibrosis by regulating fibroblast precursor cell differentiation
AIMS: Highly proliferative, CD34(+)/CD45(+) fibroblasts derived from monocytic, blood-borne precursor cells play a critical role in the development of fibrosis in a murine ischaemic/reperfusion cardiomyopathy (I/RC) model. The differentiation of human monocytes into fibroblasts in vitro occurs after...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2709463/ https://ncbi.nlm.nih.gov/pubmed/19406912 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvp135 |
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