Inhibition of Lipid A Biosynthesis as the Primary Mechanism of CHIR-090 Antibiotic Activity in Escherichia coli

समान संसाधन

• Structure of the deacetylase LpxC bound to the antibiotic CHIR-090: Time-dependent inhibition and specificity in ligand binding
  द्वारा: Barb, Adam W., और अन्य
  प्रकाशित: (2007)
• Antimicrobial Activity of CHIR-090, an Inhibitor of Lipopolysaccharide Biosynthesis, against the Burkholderia cepacia Complex
  द्वारा: Bodewits, Karin, और अन्य
  प्रकाशित: (2010)
• A slow, tight-binding inhibitor of the zinc-dependent deacetylase LpxC of lipid A biosynthesis with antibiotic activity comparable to ciprofloxacin
  द्वारा: McClerren, Amanda L., और अन्य
  प्रकाशित: (2005)
• Pathway for lipid A biosynthesis in Arabidopsis thaliana resembling that of Escherichia coli
  द्वारा: Li, Chijun, और अन्य
  प्रकाशित: (2011)
• Purification and Mutagenesis of LpxL, the Lauroyltransferase of Escherichia coli Lipid A Biosynthesis
  द्वारा: Six, David A., और अन्य
  प्रकाशित: (2008)