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Enantioselective Synthesis of Hydrobenzofuranones Using an Asymmetric Desymmetrizing Intramolecular Stetter Reaction of Cyclohexadienones

[Image: see text] A series of cyclohexadienones were synthesized by dearomatization of phenols followed by Dess-Martin oxidation. Asymmetric intramolecular Stetter reactions of these substrates provide hydrobenzofuranones in good to excellent yields and excellent stereoselectivities. Up to three ste...

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Bibliographic Details
Main Authors: Liu, Qin, Rovis, Tomislav
Format: Artigo
Language:Inglês
Published: 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709411/
https://ncbi.nlm.nih.gov/pubmed/19603085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/op600278f
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