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Asymmetric Synthesis of Hydrobenzofuranones via Desymmetrization of Cyclohexadienones using the Intramolecular Stetter Reaction

Dearomatization of phenols followed by oxidation affords cyclohexadienyloxyacetaldehydes, which produce hydrobenzofuranones via asymmetric intramolecular Stetter reaction in good to excellent yield. Quaternary as well as up to three contiguous stereocenters may be formed in good to excellent enantio...

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Detalhes bibliográficos
Main Authors: Liu, Qin, Rovis, Tomislav
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701296/
https://ncbi.nlm.nih.gov/pubmed/16492036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja058337u
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