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L-ARGININE PREVENTS METABOLIC EFFECTS OF HIGH GLUCOSE IN DIABETIC MICE

We tested the hypothesis that activation of the polyol pathway and protein kinase C (PKC) during diabetes is due to loss of NO. Our results show that after 4 weeks of streptozotocin-induced diabetes, treatment with L-arginine restored NO levels and prevented tissue accumulation of sorbitol in mice,...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: West, Matthew B., Ramana, Kota V., Kaiserova, Karin, Srivastava, Satish K., Bhatnagar, Aruni
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709283/
https://ncbi.nlm.nih.gov/pubmed/18586034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2008.06.039
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