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Aldose reductase inhibitor, fidarestat prevents high-fat diet-induced intestinal polyps in Apc(Min/+) mice
BACKGROUND: Recent epidemiological and experimental studies have shown that obesity is an important risk factor for colorectal cancer (CRC). Regular intake of high fat containing diet can promote obesity and metabolic syndrome by increasing the insulin resistance and inflammatory response which cont...
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| Publicado no: | Curr Cancer Drug Targets |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5803460/ https://ncbi.nlm.nih.gov/pubmed/28786349 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1568009617666170808105633 |
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