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Aldose reductase inhibitor, fidarestat prevents high-fat diet-induced intestinal polyps in Apc(Min/+) mice
BACKGROUND: Recent epidemiological and experimental studies have shown that obesity is an important risk factor for colorectal cancer (CRC). Regular intake of high fat containing diet can promote obesity and metabolic syndrome by increasing the insulin resistance and inflammatory response which cont...
Guardado en:
| Publicado en: | Curr Cancer Drug Targets |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5803460/ https://ncbi.nlm.nih.gov/pubmed/28786349 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1568009617666170808105633 |
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