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Energy profile and secondary structure impact shRNA efficacy
BACKGROUND: RNA interference (RNAi) is a cellular mechanism in which a short/small double stranded RNA induces the degradation of its sequence specific target mRNA, leading to specific gene silencing. Since its discovery, RNAi has become a powerful biological technique for gene function studies and...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2709270/ https://ncbi.nlm.nih.gov/pubmed/19594886 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-10-S1-S9 |
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