Modulation of Gonadotropin-Releasing Hormone Pulse Generator Sensitivity to Progesterone Inhibition in Hyperandrogenic Adolescent Girls—Implications for Regulation of Pubertal Maturation

Context: Adult women with polycystic ovary syndrome (PCOS) have decreased GnRH pulse generator sensitivity to progesterone (P)-mediated slowing. This defect is androgen mediated because it is reversed with androgen receptor blockade. Adolescent hyperandrogenism often precedes PCOS. Objective: The ai...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Blank, Susan K., McCartney, Christopher R., Chhabra, Sandhya, Helm, Kristin D., Eagleson, Christine A., Chang, R. Jeffrey, Marshall, John C.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Endocrine Society 2009
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708962/
https://ncbi.nlm.nih.gov/pubmed/19351732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2008-2606
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky