Progesterone Suppression of Luteinizing Hormone Pulse Frequency in Adolescent Girls With Hyperandrogenism: Effects of Metformin

CONTEXT: Polycystic ovary syndrome (PCOS) and adolescent hyperandrogenism (HA) are characterized by rapid luteinizing hormone (LH) pulse frequency. This partly reflects impaired gonadotropin-releasing hormone pulse generator (hypothalamic) sensitivity to progesterone (P4) negative feedback. We asses...

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Detalhes bibliográficos
Publicado no:J Clin Endocrinol Metab
Main Authors: Lundgren, Jessica A., Kim, Su Hee, Burt Solorzano, Christine M., McCartney, Christopher R., Marshall, John C.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2017
Assuntos:
Clinical Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5761484/
https://ncbi.nlm.nih.gov/pubmed/29095983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2017-02068
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