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Inhibition of Furin/Proprotein Convertase-catalyzed Surface and Intracellular Processing by Small Molecules

Furin is a ubiquitously expressed proprotein convertase (PC) that plays a vital role in numerous disease processes including cancer metastasis, bacterial toxin activation (e.g. anthrax and Pseudomonas), and viral propagation (e.g. avian influenza and human immunodeficiency virus). To identify small...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Komiyama, Tomoko, Coppola, Julia M., Larsen, Martha J., van Dort, Marcian E., Ross, Brian D., Day, Robert, Rehemtulla, Alnawaz, Fuller, Robert S.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Biochemistry and Molecular Biology 2009
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708870/
https://ncbi.nlm.nih.gov/pubmed/19332539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M901540200
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