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Inhibition of Furin/Proprotein Convertase-catalyzed Surface and Intracellular Processing by Small Molecules
Furin is a ubiquitously expressed proprotein convertase (PC) that plays a vital role in numerous disease processes including cancer metastasis, bacterial toxin activation (e.g. anthrax and Pseudomonas), and viral propagation (e.g. avian influenza and human immunodeficiency virus). To identify small...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2009
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2708870/ https://ncbi.nlm.nih.gov/pubmed/19332539 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M901540200 |
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