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Regulation of Microtubule Dynamic Instability in Vitro by Differentially Phosphorylated Stathmin
Stathmin is an important regulator of microtubule polymerization and dynamics. When unphosphorylated it destabilizes microtubules in two ways, by reducing the microtubule polymer mass through sequestration of soluble tubulin into an assembly-incompetent T2S complex (two α:β tubulin dimers per molecu...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2708860/ https://ncbi.nlm.nih.gov/pubmed/19359244 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M900343200 |
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