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Identification of Sequences in the Polysialyltransferases ST8Sia II and ST8Sia IV That Are Required for the Protein-specific Polysialylation of the Neural Cell Adhesion Molecule, NCAM

The polysialyltransferases ST8Sia II and ST8Sia IV polysialylate the glycans of a small subset of mammalian proteins. Their most abundant substrate is the neural cell adhesion molecule (NCAM). An acidic surface patch and a novel α-helix in the first fibronectin type III repeat of NCAM are required f...

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Detalhes bibliográficos
Main Authors: Foley, Deirdre A., Swartzentruber, Kristin G., Colley, Karen J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708847/
https://ncbi.nlm.nih.gov/pubmed/19336400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M809696200
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