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Progression of Murine Lupus Nephritis Is Linked to Acquired Renal Dnase1 Deficiency and Not to Up-Regulated Apoptosis

The accumulation of apoptotic cells has been suggested as a possible mechanism of nucleosome conversion into self-antigens that may both initiate autoimmune responses and participate in immune complex deposition in lupus nephritis. In this study, we analyzed both the rate of transcription of apoptos...

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Detalhes bibliográficos
Main Authors: Seredkina, Natalya, Zykova, Svetlana N., Rekvig, Ole P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708798/
https://ncbi.nlm.nih.gov/pubmed/19528352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080943
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