Involvement of WAVE Accumulation in Aβ/APP Pathology-Dependent Tangle Modification in Alzheimer’s Disease

Synaptic deficits are closely correlated with cognitive dysfunction in Alzheimer’s disease (AD), and synaptic integrity is regulated by the actin cytoskeleton. We demonstrated here that the Wiskott-Aldrich syndrome protein family verprolin-homologous protein (WAVE), a key molecule for actin assembly...

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Bibliografiska uppgifter
Huvudupphovsmän: Takata, Kazuyuki, Kitamura, Yoshihisa, Nakata, Yukinori, Matsuoka, Yasuji, Tomimoto, Hidekazu, Taniguchi, Takashi, Shimohama, Shun
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Investigative Pathology 2009
Ämnen:
Short Communication
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708790/
https://ncbi.nlm.nih.gov/pubmed/19497998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080908
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